Dual-sensitive fluorescent nanoprobes for detection of matrix metalloproteinases and low pH in a 3D tumor microenvironment-Reference-Cited by-同舟云学术

Dual-sensitive fluorescent nanoprobes for detection of matrix metalloproteinases and low pH in a 3D tumor microenvironment

Published:2022 Issue:28 Volume:10 Page:5388-5401
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Rainu Simran¹,Parameswaran Sowmya²,Krishnakumar Subramanian²^ORCID,Singh Neetu¹³^ORCID

Affiliation:

1. Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India

2. Vision Research Foundation, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Chennai 600006, Tamil Nadu, India

3. Biomedical Engineering Unit, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India

Abstract

pH/MMP-9 sensitive fluorescent nanoprobes as non-invasive imaging tool for distinguishing tumor-like microenvironments (low pH and upregulated MMP-9) from non-cancerous microenvironments in 3D microscaffolds.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB00519K

Reference66 articles.

1. Acidic Extracellular pH Promotes Experimental Metastasis of Human Melanoma Cells in Athymic Nude Mice

2. Combined Detection of Cancer Cells and a Tumor Biomarker using an Immunomagnetic Sensor for the Improvement of Prostate-Cancer Diagnosis

3. Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma

4. Prostate-specific antigen: A review of the validation of the most commonly used cancer biomarker

5. Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer

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