Targeted treatment of gouty arthritis by biomineralized metallic nanozyme-mediated oxidative stress-mitigating nanotherapy

Author:

Mohapatra Adityanarayan1ORCID,Mohanty Ayeskanta1,Sathiyamoorthy Padmanaban1,Chahal Sahil1,Vijayan Veena1,Rajendrakumar Santhosh Kalash2ORCID,Park In-Kyu1ORCID

Affiliation:

1. Department of Biomedical Science, BK21 PLUS Center for Creative Biomedical Scientists, Chonnam National University Medical School, Gwangju 61469, South Korea

2. Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK

Abstract

Targeted delivery of ceria nanozymes depletes oxidative stress in inflammatory macrophage cells and alleviates gouty arthritis symptoms by suppressing inflammatory signals.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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