Potential mechanisms mediating the protective effects of a peptide from walnut (Juglans mandshuricaMaxim.) against hydrogen peroxide induced neurotoxicity in PC12 cells

Author:

Liu Chunlei12345,Guo Yong12345,Zhao Fanrui12345,Qin Hanxiong12345,Lu Hongyan12345,Fang Li12345,Wang Ji12345,Min Weihong12345ORCID

Affiliation:

1. College of Food Science and Engineering

2. Jilin Agricultural University

3. Changchun 130118

4. P.R. China

5. National Engineering Laboratory of Wheat and Corn Deep Processing

Abstract

A novel neuroprotective peptide EVSGPGLSPN, which was identified from walnut protein hydrolysates, protected PC12 cells by blocking the NF-κB/caspase pathways.

Funder

National High-tech Research and Development Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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