An adaptable soft-mold embossing process for fabricating optically-accessible, microfeature-based culture systems and application toward liver stage antimalarial compound testing-Reference-Cited by-同舟云学术

An adaptable soft-mold embossing process for fabricating optically-accessible, microfeature-based culture systems and application toward liver stage antimalarial compound testing

Published:2020 Issue:6 Volume:20 Page:1124-1139
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Maher Steven P.¹²³⁴⁵^ORCID,Conway Amy J.¹²³⁴⁵,Roth Alison¹²³⁴⁵^ORCID,Adapa Swamy R.¹²³⁴⁵,Cualing Phillip¹²³⁴⁵,Andolina Chiara⁶⁷⁸⁹¹⁰,Hsiao James¹¹¹²¹³,Turgeon Jessica¹²³⁴⁵,Chaumeau Victor⁶⁷⁸⁹¹⁰,Johnson Myles¹²³⁴⁵,Palmiotti Chris¹¹¹²¹³,Singh Naresh¹²³⁴⁵,Barnes Samantha J.¹²³⁴⁵^ORCID,Patel Raahil¹²³⁴⁵,Van Grod Virginia¹¹¹²¹³,Carter Robert¹²³⁴⁵,Sun H.-C. Steve¹¹¹²¹³,Sattabongkot Jetsumon¹⁴⁸⁹¹⁵¹⁶,Campo Brice¹⁷¹⁸¹⁹^ORCID,Nosten François⁶⁷⁸⁹¹⁰^ORCID,Saadi Wajeeh M.¹¹¹²¹³,Adams John H.¹²³⁴⁵^ORCID,Jiang Rays H. Y.¹²³⁴⁵^ORCID,Kyle Dennis E.¹²³⁴⁵^ORCID

Affiliation:

1. Center for Global Health and Infectious Diseases Research

2. Department of Global Health

3. College of Public Health

4. University of South Florida

5. Tampa

6. Shoklo Malaria Research Unit

7. Mahidol Oxford Research Unit

8. Faculty of Tropical Medicine

9. Mahidol University

10. Mae Sot

11. Charles Stark Draper Laboratory

12. Cambridge

13. USA

14. Mahidol Vivax Research Unit

15. Bangkok

16. Thailand

17. Medicines for Malaria Venture

18. Geneva

19. Switzerland

Abstract

An intrahepatic Plasmodium vivax liver stage schizont and hypnozoite develop in a microfeature-based, 384-well culture system for primary human hepatocytes.

Funder

American Cancer Society

Bill and Melinda Gates Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/C9LC00921C

Reference65 articles.

1. Multi-Organs-on-Chips: Towards Long-Term Biomedical Investigations

2. Automated cell culture in high density tubeless microfluidic device arrays