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Combination targeting of ‘platelets + fibrin’ enhances clot anchorage efficiency of nanoparticles for vascular drug delivery

  • Published:2020 Issue:41 Volume:12 Page:21255-21270
  • ISSN:2040-3364
  • Container-title:Nanoscale
  • language:en
  • Short-container-title:Nanoscale

Author:

Sun Michael1234,Miyazawa Kenji1234,Pendekanti Tejal564,Razmi Amaya564,Firlar Emre7894,Yang Stephanie1234,Shokuhfar Tolou7894ORCID,Li Oliver1011124,Li Wei1011124,Sen Gupta Anirban1234ORCID

Affiliation:

1. Case Western Reserve University

2. Department of Biomedical Engineering

3. Cleveland

4. USA

5. Hathaway Brown School

6. Shaker Heights

7. University of Illinois at Chicago

8. Department of Bioengineering

9. Chicago

10. Marshall University

11. Department of Biomedical Sciences

12. Huntington

Abstract

Occlusive thrombosis is a central pathological event in heart attack, stroke, thromboembolism, etc.

Funder

National Heart, Lung, and Blood Institute

National Science Foundation

National Center for Research Resources

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Reference60 articles.

1. https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)

2. Arterial thrombus formation in cardiovascular disease

3. Arterial thrombosis—insidious, unpredictable and deadly

4. Venous thrombosis

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