Screening of neuraminidase inhibitors from the leaves of Syringa velutina Kom. via compound fractionation and in vitro activity evaluation
Author:
Affiliation:
1. Central Laboratory
2. Changchun Normal University
3. Changchun 130032
4. China
5. Department of Pharmacy
6. Affiliated Hospital to Changchun University of Chinese Medicine
7. Changchun 130021
Abstract
A novel hyphenated technique comprised of circulating ultrasound-assisted extraction (CUAE) coupled with an online solvent concentration tank (SCT), centrifugal partition chromatography (CPC), ultra-high performance liquid chromatography (UPLC), and mass spectrometry (MS) was established.
Funder
Natural Science Foundation of Jilin Province
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/AY/C6AY02922A
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1. Desorption electrospray ionization reactions between host crown ethers and the influenza neuraminidase inhibitor oseltamivir for the rapid screening of Tamiflu®
2. A Novel Lung Explant Model for the Ex Vivo Study of Efficacy and Mechanisms of Anti-Influenza Drugs
3. Integration of neuraminidase inhibitor assay into a single-step operation using a combinable poly(dimethylsiloxane) capillary sensor
4. Post-marketing safety and effectiveness evaluation of the intravenous anti-influenza neuraminidase inhibitor peramivir (II): A pediatric drug use investigation
5. A chemotaxonomic survey of flavonoids in leaves of the Oleaceae
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