How to obtain Pt(iv) complexes suitable for conjugation to nanovectors from the oxidation of [PtCl(terpyridine)]+-Reference-Cited by-同舟云学术

How to obtain Pt(iv) complexes suitable for conjugation to nanovectors from the oxidation of [PtCl(terpyridine)]+

Published:2017 Issue:31 Volume:46 Page:10246-10254
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Gabano E.¹²³⁴^ORCID,Perin E.¹²³⁴^ORCID,Fielden C.⁵⁶⁷⁸,Platts J. A.⁵⁶⁷⁸^ORCID,Gallina A.¹²³⁴^ORCID,Rangone B.¹²³⁴^ORCID,Ravera M.¹²³⁴^ORCID

Affiliation:

1. Dipartimento di Scienze e Innovazione Tecnologica

2. Università del Piemonte Orientale

3. 15121 Alessandria

4. Italy

5. School of Chemistry

6. Cardiff University

7. Cardiff CF10 3AT

8. UK

Abstract

Pt(ii)-Terpyridine complexes were oxidized with difficulty to Pt(iv) prodrugs, loaded onto silica nanovectors and in vitro tested for their antiproliferative properties.

Funder

Compagnia di San Paolo

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/DT/C7DT01706E

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1. Studies on the antitumor activity of group VIII transition metal complexes. Part I. Platinum (II) complexes

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4. Chemical and biological properties of a new series of cis-diammineplatinum(II) antitumor agents containing three nitrogen donors: cis-[Pt(NH3)2(N-donor) Cl]+

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