An indium-111-labelled membrane-targeted peptide for cell tracking with radionuclide imaging-Reference-Cited by-同舟云学术

An indium-111-labelled membrane-targeted peptide for cell tracking with radionuclide imaging

Published:2023 Issue:1 Volume:4 Page:65-73
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Pruller Johanna¹²,Pham Truc Thuy²^ORCID,Blower Julia E.²^ORCID,Charoenphun Putthiporn²³,Volpe Alessia²,Sunassee Kavitha²,Mullen Gregory E. D.²,Blower Philip J.²^ORCID,Smith Richard A. G.⁴,Ma Michelle T.²^ORCID

Affiliation:

1. Randall Division of Cell and Molecular Biophysics, King's College London, UK

2. School of Biomedical Engineering and Imaging Sciences, King's College London, St Thomas’ Hospital, London, UK

3. Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

4. MRC Centre for Transplantation, King's College London, Guy's Hospital, London, UK

Abstract

An indium-111-labelled peptide binds to myeloma cells, enabling SPECT imaging of myeloma cell accumulation in lungs after intravenous administration. This is the first report of a radiolabelled cell-membrane binding peptide for cell tracking.

Funder

Wellcome

Cancer Research UK

Engineering and Physical Sciences Research Council

National Institute for Health and Care Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CB/D2CB00164K

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