A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging-Reference-Cited by-同舟云学术

A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging

Published:2022 Issue:10 Volume:3 Page:1251-1259
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Fernandez Antonio¹²^ORCID,Kielland Nicola¹³,Makda Ashraff⁴,Carragher Neil O.⁴,González-García M. Carmen⁵^ORCID,Espinar-Barranco Laura⁵,González-Vera Juan A.⁵^ORCID,Orte Angel⁵^ORCID,Lavilla Rodolfo³^ORCID,Vendrell Marc¹^ORCID

Affiliation:

1. Centre for Inflammation Research, The University of Edinburgh, Edinburgh, UK

2. Dpt Organic Chemistry, Faculty of Chemistry, University of Murcia, Spain

3. Laboratory of Medicinal Chemistry, Faculty of Pharmacy and Institute of Biomedicine (IBUB), University of Barcelona, Spain

4. Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK

5. Nanoscopy-UGR Laboratory, Facultad de Farmacia, Universidad de Granada, Granada, Spain

Abstract

By combining synthetic multicomponent reactions and cell-based screenings, we identified NIRBD-62c as a multimodal probe for STED and fluorescence lifetime imaging of the vesicular traffic between intracellular compartments and the plasma membrane.

Funder

Royal Society

H2020 European Research Council

Ministerio de Ciencia e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CB/D2CB00168C

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1. Intracellular trafficking and secretion of inflammatory cytokines