A carbon dot-based fluorescent nanoprobe for the associated detection of iron ions and the determination of the fluctuation of ascorbic acid induced by hypoxia in cells and in vivo

Author:

Huang Yan12345,He Na678910,Kang Qi12345,Shen Dazhong12345ORCID,Wang Xiaoyan678910,Wang Yunqing678910,Chen Lingxin678910ORCID

Affiliation:

1. College of Chemistry

2. Chemical Engineering and Materials Science

3. Key Laboratory of Molecular and Nano Probes

4. Ministry of Education

5. Shandong Normal University

6. CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation

7. The Research Center for Coastal Environmental Engineering and Technology

8. Yantai Institute of Coastal Zone Research

9. Chinese Academy of Sciences

10. Yantai 264003

Abstract

The fluorescent nanoprobe CD-DB complexation with iron ions was used to determine the fluctuation of ascorbic acid induced by hypoxia in living cells, zebrafish and mice.

Funder

National Natural Science Foundation of China

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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