On-a-chip tryptic digestion of transthyretin: a step toward an integrated microfluidic system for the follow-up of familial transthyretin amyloidosis-Reference-Cited by-同舟云学术

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On-a-chip tryptic digestion of transthyretin: a step toward an integrated microfluidic system for the follow-up of familial transthyretin amyloidosis

Published:2018 Issue:5 Volume:143 Page:1077-1086
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Bataille Jeanne¹²³⁴⁵,Viodé Arthur⁶⁷⁸⁹¹⁰,Pereiro Iago¹¹¹²¹³¹⁴⁵^ORCID,Lafleur Josiane P.¹⁵¹⁶¹⁷¹⁸^ORCID,Varenne Fanny¹²³⁴⁵,Descroix Stéphanie¹¹¹²¹³¹⁴⁵^ORCID,Becher François⁶⁷⁸⁹¹⁰,Kutter Jörg P.¹⁵¹⁶¹⁷¹⁸,Roesch Camille¹⁹²⁰⁵,Poüs Christian²¹²²²³²⁴⁵,Taverna Myriam¹²³⁴⁵,Pallandre Antoine¹²³⁴⁵,Smadja Claire¹²³⁴⁵^ORCID,Le Potier Isabelle¹²³⁴⁵

Affiliation:

1. Faculté de Pharmacie

2. Université Paris-Sud

3. Université Paris-Saclay

4. Châtenay-Malabry

5. France

6. Service de Pharmacologie et d'Immunoanalyse (SPI)

7. Laboratoire d'Etude du Métabolisme des Médicaments

8. CEA

9. INRA

10. Université Paris Saclay

11. CNRS

12. UMR 168

13. Institut Curie

14. Paris

15. Department of Pharmacy

16. University of Copenhagen

17. Copenhagen

18. Denmark

19. IZON Sciences Ldt

20. Lyon

21. Hôpital Antoine Béclère

22. AP-HP

23. Service de Biochimie

24. Clamart

Abstract

TTR digestion on TE-chip: production of a fragment of interest allowing the therapeutic follow-up of the familial transthyretin amyloidosis.

Funder

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/AN/C7AN01737E

Reference49 articles.

1. Transthyretin (TTR) Cardiac Amyloidosis

2. Guideline of transthyretin-related hereditary amyloidosis for clinicians

3. Diagnosis, Prognosis, and Therapy of Transthyretin Amyloidosis

4. Fibril in senile systemic amyloidosis is derived from normal transthyretin.

5. Familial amyloid polyneuropathy

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