Multifunctional ATRP based pH responsive polymeric nanoparticles for improved doxorubicin chemotherapy in breast cancer by proton sponge effect/endo-lysosomal escape-Reference-Cited by-同舟云学术

Multifunctional ATRP based pH responsive polymeric nanoparticles for improved doxorubicin chemotherapy in breast cancer by proton sponge effect/endo-lysosomal escape

Published:2015 Issue:11 Volume:6 Page:2115-2132
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Lale Shantanu V.¹²³⁴⁵,Kumar Arun¹²³⁴⁵,Naz Farhat⁶⁷⁸⁴,Bharti Alok C.⁹¹⁰¹¹⁴,Koul Veena¹²³⁴⁵

Affiliation:

1. Centre for Biomedical Engineering

2. Indian Institute of Technology Delhi

3. New Delhi 110016

4. India

5. Biomedical Engineering Unit

6. Department of Pathology

7. All India Institute of Medical Sciences

8. New Delhi 110029

9. Division of Molecular Oncology

10. Institute of Cytology and Preventive Oncology

11. Noida 201301

Abstract

Folic acid and trastuzumab functionalized pH responsive polymeric nanoparticles for intracellular doxorubicin delivery in breast cancer.

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/PY/C4PY01698J

Reference61 articles.

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4. Nanoparticles in cancer therapy and diagnosis

5. Targeting and anti-tumor effect of folic acid-labeled polymer–Doxorubicin conjugates with pH-sensitive hydrazone linker

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