Application of sugar-containing biomass: one-step synthesis of 2-furylglyoxylic acid and its derivatives from a vitamin C precursor

Author:

Chen Jiao1,Zhu Zhenhua1,Cai Jiali2,Cao Mengru1,Sha Feng3,Tao Sha1,Yang Hao1,Gan Haifeng1ORCID,Wu Hongli1,Cao Fei1ORCID,Zhao Lili2ORCID,Ouyang Pingkai1

Affiliation:

1. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 South Puzhu Road, Nanjing, 211816, P. R. China

2. Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, 30 South Puzhu Road, Nanjing, 211816, P. R. China

3. Suzhou Cornigs Polyols Co., Ltd, 1183 Wuzhong Avenue, Suzhou, 215000, P. R. China

Abstract

A novel pathway is demonstrated for preparing the high-value pharmaceutical intermediate 2-furylglyoxylic acid from 2-keto-l-gulonic acid, a bio-based sugar acid, via dehydration.

Funder

National Key Research and Development Program of China

Six Talent Peaks Project in Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference52 articles.

1. S.Mailaram , P.Kumar , A.Kunamalla , P.Saklecha and S. K.Maity , Biomass, biorefinery, and biofuels , Elsevier , Netherlands , 2021 , vol. 43

2. Biomass-based chemical looping technologies: the good, the bad and the future

3. A sustainable wood biorefinery for low–carbon footprint chemicals production

4. V.Varho , A.Rautiainen , M.Peltonen , J.Niemi and U.Ovaska , Biopaths to Carbon Neutrality , Ministry of Agriculture and Forestry , Finland , 2018 , vol. 3

5. From waste to sustainable industry: How can agro-industrial wastes help in the development of new products?

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