Computational investigation of the human SOD1 mutant, Cys146Arg, that directs familial amyotrophic lateral sclerosis-Reference-Cited by-同舟云学术

Computational investigation of the human SOD1 mutant, Cys146Arg, that directs familial amyotrophic lateral sclerosis

Published:2017 Issue:8 Volume:13 Page:1495-1503
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Srinivasan E.¹²³⁴⁵,Rajasekaran R.¹²³⁴⁵^ORCID

Affiliation:

1. Bioinformatics Lab

2. Department of Biotechnology

3. School of Bio Sciences and Technology

4. VIT University

5. Vellore 632014

Abstract

Molecular dynamics simulations along with the computational predictions used to assess the protein structural characterization as well as the conformational preferences of the monomeric native and mutant SOD1.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MB/C7MB00106A

Reference51 articles.

1. Formation and transfer of disulphide bonds in living cells

2. Disulfide Scrambling Describes the Oligomer Formation of Superoxide Dismutase (SOD1) Proteins in the Familial Form of Amyotrophic Lateral Sclerosis

3. The Biology of Oxygen Radicals

4. Structure and dynamics of copper-free SOD: The protein before binding copper

5. SOD1 and Amyotrophic Lateral Sclerosis: Mutations and Oligomerization

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Computational insight into in silico analysis and molecular dynamics simulation of the dimer interface residues of ALS-linked hSOD1 forms in apo/holo states: a combined experimental and bioinformatic perspective;3 Biotech;2023-02-21

2. Comparative analyses and molecular videography of MD simulations on WT human SOD1;Computational and Theoretical Chemistry;2022-11

3. Biochemical and biophysical properties of the novel ALS-linked hSOD1 mutants: an experimental study accompanied by in silico analysis;Journal of the Iranian Chemical Society;2022-09-13

4. A Review On Huntington Protein: Insight Into Protein Aggregation and Therapeutic Interventions;Current Drug Metabolism;2022-04

5. Computer analysis of the relation between hydrogen bond stability in SOD1 mutants and the survival time of amyotrophic lateral sclerosis patients;Journal of Molecular Graphics and Modelling;2022-01