Cyclosporine A loaded self-nanoemulsifying drug delivery system (SNEDDS): implication of a functional excipient based co-encapsulation strategy on oral bioavailability and nephrotoxicity

Author:

Jain Sanyog12345,Kambam Sindhu12345,Thanki Kaushik12345,Jain Amit K.12345

Affiliation:

1. Centre for Pharmaceutical Nanotechnology

2. Department of Pharmaceutics

3. National Institute of Pharmaceutical Education and Research (NIPER)

4. Mohali

5. India

Abstract

The present work focusses on the formulation development and evaluation of a functional excipient, a vitamin E TPGS loaded self-nanoemulsifying drug delivery system, for improving the deliverability and safety profile of cyclosporine A.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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5. Investigation of the pharmacokinetics of cyclosporine in patients following long-term administration after a kidney transplant: comparison of neoral and sandimmune

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