Melting temperature of molecular beacons as an indicator of the ligase detection reaction for multiplex detection of point mutations-Reference-Cited by-同舟云学术

Melting temperature of molecular beacons as an indicator of the ligase detection reaction for multiplex detection of point mutations

Published:2015 Issue:10 Volume:7 Page:4225-4230
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Luo Weihao¹²³⁴⁵,Zhou Dianming⁶⁷⁸⁹⁵,Luo Dixian¹⁰¹¹¹²⁵,Jiang Jianhui⁶⁷⁸⁹⁵,Xu Xiangmin¹²³⁴⁵

Affiliation:

1. Department of Medical Genetics

2. School of Basic Medical Sciences

3. Southern Medical University

4. Guangzhou

5. P. R. China

6. State Key Laboratory for Chemo/Biosensing and Chemometrics

7. College of Chemistry and Chemical Engineering

8. Hunan University

9. Changsha

10. Institute of Translational Medicine

11. First People's Hospital of Chenzhou affiliated to Southern Medical University

12. Chenzhou

Abstract

A novel strategy based on the ligase detection reaction (LDR) using the melting temperature of molecular beacons as the indicator is presented for the multiplex detection of gene mutations.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AY/C5AY00475F

Reference24 articles.

1. Two Novel Methods for Rapid Detection and Quantification of DNMT3A R882 Mutations in Acute Myeloid Leukemia

2. Mutation analysis of ATP7B gene in Turkish Wilson disease patients: Identification of five novel mutations

3. The Role of Testing forBRCA1andBRCA2Mutations in Cancer Prevention

4. α-thalassaemia

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Real-time detection of SARS-CoV-2 in clinical samples via ultrafast ligation-dependent RNA transcription amplification;Analytical Methods;2023

2. All-in-one approaches for rapid and highly specific quantifcation of single nucleotide polymorphisms based on ligase detection reaction using molecular beacons as turn-on probes;Talanta;2021-03

3. Thermus thermophilus DNA Ligase Connects Two Fragments Having Exceptionally Short Complementary Termini at High Temperatures;Biochemistry;2019-12-30