Dual detection of nafcillin using a molecularly imprinted polymer-based platform coupled to thermal and fluorescence read-out

Author:

Hudson Alexander D.1234,Jamieson Oliver1234,Crapnell Robert D.5674ORCID,Rurack Knut891011ORCID,Soares Thais C. C.1213141516,Mecozzi Francesco5674,Laude Alex11734,Gruber Jonas1819141516ORCID,Novakovic Katarina1234,Peeters Marloes1234ORCID

Affiliation:

1. Newcastle University

2. School of Engineering

3. Newcastle Upon Tyne

4. UK

5. Manchester Metropolitan University

6. Faculty of Science and Engineering

7. Manchester

8. Chemical and Optical Sensing Division

9. Bundesanstalt für Materialforschung und -prüfung (BAM)

10. 12489 Berlin

11. Germany

12. Departamento de Engenharia Química

13. Escola Politécnica

14. Universidade de São Paulo

15. São Paulo

16. Brazil

17. Bioimaging Unit

18. Departamento de Química Fundamental

19. Instituto de Química

Abstract

Reported here is the production of molecularly imprinted polymer (MIP) films, integrating a fluorescent moiety that serves as both an element for template interaction and signalling, for the thermal and optical detection of the antibiotic nafcillin.

Funder

Engineering and Physical Sciences Research Council

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Microbiology

Reference49 articles.

1. Origins and Evolution of Antibiotic Resistance

2. Interagency Coordination Group on Antimicrobial Resistance, 2019. No time to wait: securing the future from drug-resistant infections report to the secretary-general of the United Nations, World Health Organisation. https://www.who.int/antimicrobial-resistance/interagency-coordination-group/IACG_final_report_EN.pdf?ua=1

3. World Health Organization, 2018. WHO Report on Surveillance of Antibiotic Consumption. https://www.who.int/docs/default-source/documents/no-time-to-wait-securing-the-future-from-drug-resistant-infections-en.pdf?sfvrsn=5b424d7_6

4. European Commission, Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. Off. J. Eur. Union L15, 2010, pp. 1–72

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