Dicarboxylato platinum(ii) complexes containing dimethyl sulfoxide and triazolopyrimidine as potential anticancer agents: synthesis, structural and biological studies in solution
Author:
Affiliation:
1. Faculty of Chemistry
2. Nicolaus Copernicus University in Toruń
3. 87-100 Toruń
4. Poland
5. National Institutes of Medicines
6. 00-725 Warszawa
7. Institutes of Organic Chemistry
8. Polish Academic of Science
Abstract
N,O,S-donors platinum(ii) complexes were synthesized and well characterized. We demonstrate that modification of coordination sphere by insertion of dmso molecule and bulky triazolopyrimidine ligand is good direction for the design effective less toxic platinum(ii) complexes.
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ01199K
Reference49 articles.
1. Clinical Perspectives on Platinum Resistance
2. New clues for platinum antitumor chemistry: Kinetically controlled metal binding to DNA
3. Metal-Ligand Exchange Kinetics in Platinum and Ruthenium Complexes
4. Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects
5. Molecular aspects of resistance to antitumor platinum drugs
Cited by 21 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Anticancer Study on IrIII and RhIII Half-Sandwich Complexes with the Bipyridylsulfonamide Ligand;Inorganic Chemistry;2024-01-04
2. Pd(Ii) and Pt(Ii) Thiophene-Based Thiosemicarbazones: Synthesis, Properties, and Anticancer Studies;2024
3. Novel arylplatinum complexes with 2,2′‐dimethyl‐4,4′‐bithiazole: Synthesis, characterization, single crystal structure determination, and investigation of CT‐DNA interaction;Applied Organometallic Chemistry;2023-02-11
4. Anticancer property and normal cell toxicity profile of pyrrolidine‐based platinum (II) complexes: Their DNA, BSA interaction, and molecular docking;Applied Organometallic Chemistry;2022-08-25
5. Synthesis, crystal structure and spectroscopic characterization of new anionic iridium(III) complexes and their interaction with biological targets;Polyhedron;2022-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3