Affiliation:
1. State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China
Abstract
Development of a highly diastereoselective synthetic approach to α-substituted phosphonates via CAMDOL-derived P-substrates by sequential deprotonation with LiHMDS and alkylation/arylation with RI to afford a range of structurally diverse products in up to 92% yields and 99 : 1 d.r.
Publisher
Royal Society of Chemistry (RSC)