Tracking the cellular uptake and phototoxicity of Ru(<scp>ii</scp>)-polypyridyl-1,8-naphthalimide Tröger's base conjugates-Reference-Cited by-同舟云学术

Tracking the cellular uptake and phototoxicity of Ru(ii)-polypyridyl-1,8-naphthalimide Tröger's base conjugates

Published:2024 Issue:4 Volume:5 Page:344-359
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Bright Sandra A.¹²,Erby MariaLuisa¹,Poynton Fergus E.²,Monteyne Daniel³,Pérez-Morga David³⁴,Gunnlaugsson Thorfinnur²⁵^ORCID,Williams D. Clive¹,Elmes Robert B. P.⁵⁶⁷^ORCID

Affiliation:

1. School of Biochemistry and Immunology, Biomedical Sciences Institute, Trinity College, Dublin 2, Ireland

2. School of Chemistry, Centre for Synthesis and Chemical Biology, Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland

3. Laboratoire de Parasitologie Moléculaire, IBMM-DBM Université Libre de Bruxelles, Gosselies, Belgium

4. Center for Microscopy and Molecular Imaging CMMI Université Libre de Bruxelles, Gosselies, Belgium

5. Synthesis and Solid State Pharmaceutical Centre (SSPC), University of Limerick, Ireland

6. Department of Chemistry, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Ireland

7. Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland

Abstract

Ru(ii)-Polypyridyl-1,8-naphthalimide Tröger's bases have undergone detailed biological profiling to unravel their mechanism of cellular uptake, cellular trafficking and cellular responses to photoexcitation.

Funder

Science Foundation Ireland

Irish Research Council

European Regional Development Fund

Higher Education Authority

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CB/D3CB00206C

Reference125 articles.

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2. Synthesis, Photophysical, and DNA Binding Studies of Fluorescent Tröger’s Base Derived 4-Amino-1,8-naphthalimide Supramolecular Clefts

3. Synthesis, photophysical and cytotoxicity evaluations of DNA targeting agents based on 3-amino-1,8-naphthalimide derived Tröger's bases

4. A supramolecular Tröger's base derived coordination zinc polymer for fluorescent sensing of phenolic-nitroaromatic explosives in water

5. Supramolecular coordination polymers using a close to ‘V-shaped’ fluorescent 4-amino-1,8-naphthalimide Tröger's base scaffold