Polyphenol-based nanoplatform for MRI/PET dual-modality imaging guided effective combination chemotherapy

Author:

Wang Jingjing12345,Sang Wei67894,Yang Zhen510111213,Shen Zheyu510111213ORCID,Wang Zhantong510111213,Jacobson Orit510111213,Chen Yundai1234,Wang Yong1415164,Shao Mingyan1415164,Niu Gang510111213,Dai Yunlu67894ORCID,Chen Xiaoyuan510111213ORCID

Affiliation:

1. Department of Cardiology

2. Chinese PLA General Hospital

3. Beijing 100853

4. China

5. Laboratory of Molecular Imaging and Nanomedicine (LOMIN)

6. Cancer Centre

7. Faculty of Health Sciences

8. University of Macau

9. Macau SAR 999078

10. National Institute of Biomedical Imaging and Bioengineering (NIBIB)

11. National Institutes of Health (NIH)

12. Bethesda

13. USA

14. School of Life Science

15. Beijing University of Chinese Medicine

16. Beijing 100029

Abstract

A smart nanoplatform with doxorubicin (DOX) and simvastatin (SV) was fabricated by encapsulating both drugs in a polyphenol-based polymer for chemotherapy and MRI/PET imaging.

Funder

Fundo para o Desenvolvimento das Ciências e da Tecnologia

National Institute of Biomedical Imaging and Bioengineering

Universidade de Macau

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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