Dual-crosslinked hydrogel microwell system for formation and culture of multicellular human adipose tissue-derived stem cell spheroids
Author:
Affiliation:
1. Department of Biomedical Engineering
2. Case Western Reserve University
3. Cleveland
4. USA
5. Department of Orthopaedic Surgery
Abstract
A novel biodegradable, biocompatible alginate-PEG hydrogel microwell system was developed with tailorable microwell physical and biochemical properties to control the uniform formation and behavior of three-dimensional multicellular human adipose tissue-derived stem cell spheroids.
Funder
National Institute of Dental and Craniofacial Research
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2016/TB/C6TB00064A
Reference48 articles.
1. Comparison of Proliferative and Multilineage Differentiation Potential of Human Mesenchymal Stem Cells Derived from Umbilical Cord and Bone Marrow
2. Multilineage Potential of Adult Human Mesenchymal Stem Cells
3. Isolation of Mesenchymal Stem Cells of Fetal or Maternal Origin from Human Placenta
4. Multilineage Cells from Human Adipose Tissue: Implications for Cell-Based Therapies
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