An automatable platform for genotoxicity testing of nanomaterials based on the fluorometric γ-H2AX assay reveals no genotoxicity of properly surface-shielded cadmium-based quantum dots-Reference-Cited by-同舟云学术

An automatable platform for genotoxicity testing of nanomaterials based on the fluorometric γ-H2AX assay reveals no genotoxicity of properly surface-shielded cadmium-based quantum dots

Published:2019 Issue:28 Volume:11 Page:13458-13468
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Geißler D.¹²³⁴^ORCID,Wegmann M.¹²³⁴⁵,Jochum T.⁶⁷⁴,Somma V.⁵⁸⁹⁴,Sowa M.⁵⁸⁹⁴,Scholz J.⁵⁸⁹⁴,Fröhlich E.¹⁰¹¹¹²¹³^ORCID,Hoffmann K.¹²³⁴^ORCID,Niehaus J.¹⁰¹¹¹²¹³,Roggenbuck D.⁵⁸⁹⁴¹⁴,Resch-Genger U.¹²³⁴^ORCID

Affiliation:

1. Bundesanstalt für Materialforschung und -prüfung (BAM)

2. Division 1.2 Biophotonics

3. 12489 Berlin

4. Germany

5. MEDIPAN GmbH

6. Fraunhofer-Zentrum für Angewandte Nanotechnologie CAN

7. 20146 Hamburg

8. Ludwig-Erhard-Ring 3

9. 15827 Dahlewitz

10. Medizinische Universität Graz

11. Zentrum für Medizinische Forschung (ZMF)

12. 8010 Graz

13. Austria

14. Institute of Biotechnology

Abstract

The genotoxic potential of citrate-stabilized gold nanoparticles, micellar encapsulated iron oxide nanoparticles, and cadmium-based semiconductor quantum dots with different shell compositions was tested using the automated microscope system AKLIDES.

Funder

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NR/C9NR01021A

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