Synthesis of 2-aminopropyl benzopyran derivatives as potential agents against triple-negative breast cancer-Reference-Cited by-同舟云学术

Synthesis of 2-aminopropyl benzopyran derivatives as potential agents against triple-negative breast cancer

Published:2023 Issue:11 Volume:14 Page:2327-2341
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

García Ainhoa¹²^ORCID,Torres-Ruiz Sandra²,Vila Laura²^ORCID,Villarroel-Vicente Carlos¹²,Bernabeu Álvaro¹,Eroles Pilar²³⁴,Cabedo Nuria¹²^ORCID,Cortes Diego¹^ORCID

Affiliation:

1. Department of Pharmacology, University of Valencia, 46100 Valencia, Spain

2. Institute of Health Research-INCLIVA, University Clinic Hospital of Valencia, 46010 Valencia, Spain

3. Department of Physiology, University of Valencia, 46010 Valencia, Spain

4. Center for Biomedical Network Research on Cancer (CIBERONC), 28019 Madrid, Spain

Abstract

Synthesis of three series of 2-aminopropyl derivatives bearing a benzopyran nucleus was performed to evaluate their performance against triple-negative breast cancer cell lines (MDA-MB-231 and MDA-MB-436) and normal breast epithelial cells (MCF10A).

Funder

Instituto de Salud Carlos III

Generalitat Valenciana

European Social Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D3MD00385J

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