Water–DMSO-promoted one-pot synthesis of two new series of dihydropyrrolo[2,3-h]quinolines-Reference-Cited by-同舟云学术

Water–DMSO-promoted one-pot synthesis of two new series of dihydropyrrolo[2,3-h]quinolines

Published:2020 Issue:2 Volume:18 Page:215-219
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liao Hui¹²³⁴⁵,Zhu Qiuhua¹²³⁴⁵^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of New Drug Screening

2. School of Pharmaceutical Sciences

3. Southern Medical University

4. Guangzhou 510515

5. China

Abstract

Two new series of dihydropyrrolo[2,3-h]quinolines 4 and 6 were synthesized via a three-component reaction synergistically activated by water and DMSO, and new pyrrolo[2,3-h]quinolines 10 can be obtained by oxidation of 4 using Cu(NO₃)₂ as oxidant.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/C9OB02342A

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3. Amidic Coupling in the Synthesis of Pyrroloquinoline 4‐ and 9‐Carboxamides as Potential STAT3 Inhibitors