Exploitation of flow-based procedures for reagentless hydrochlorothiazide determination and accelerated degradation studies of pharmaceutical preparations

Author:

Maringolo Vivian123,Aleixo Fernanda Caroline123,Carvalho Alexandre Zatkovskis123,Rocha Diogo Librandi123ORCID

Affiliation:

1. Center on Natural and Human Sciences

2. Federal University of ABC

3. Brazil

Abstract

Reagentless, fast and inexpensive in-line hydrochlorothiazide determination, and reduced time for degradation studies, from hours to a few minutes.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference24 articles.

1. World Health Organization , https://www.who.int/health-topics/hypertension , World Heal. Organ , 2019 , access in: 11/05/2019

2. Hydroclorothiazide , https://Pubchem.Ncbi.Nlm.Nih.Gov/Compound/Hydrochlorothiazide#section=Substances , 2019 , access in: 11/05/2019

3. A Validated Stability-Indicating LC Method for Simultaneous Determination of Enalapril and Hydrochlorothiazide in Pharmaceutical Samples

4. Brazil Health Ministry, ANVISA , Brazilian Phamacopeia , Brazil , 6th edn, 2019

5. Flow injection analysis of pharmaceuticals

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