Domino alkyne insertion/aldol reaction/aromatization of 2-alkynyl indole-3-carbaldehyde with 1,3-diketones: entry to 2-indolyl phenols-Reference-Cited by-同舟云学术

Domino alkyne insertion/aldol reaction/aromatization of 2-alkynyl indole-3-carbaldehyde with 1,3-diketones: entry to 2-indolyl phenols

Published:2023 Issue:5 Volume:21 Page:1046-1055
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Raji Reddy Chada¹²^ORCID,Nair Karna¹²,Patil Amol D.¹²^ORCID,Donthiri Ramachandra Reddy¹^ORCID,Grée René³^ORCID

Affiliation:

1. Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad - 500007, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201 002, India

3. University of Rennes, Institut des Sciences Chimiques de Rennes (ISCR), CNRS UMR 6226, F-35000 Rennes, France

Abstract

Base mediated metal-free construction of 2-indolyl phenols was developed from 2-alkynyl indole-3-carbaldehyde. The obtained products led to a unique strategy to access dihydrochromeno[4,3-b]indoles.

Funder

Council of Scientific and Industrial Research, India

Centre National de la Recherche Scientifique

Université de Rennes 1

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB02025D

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