Simultaneous determination of cyanide and thiocyanate in swine plasma by high-performance liquid chromatography with fluorescence detection based on a novel D–π–A carbazole-based turn-on fluorescence labeling reagent

Author:

Luo Pengjie1234,Yu Yanxin5674,Wu Di894,Li Xiuting1011124,Dai Chunji5674,Chen Xuefeng5674,Li Guoliang10111245ORCID,Wu Yongning1234

Affiliation:

1. Key Laboratories of Chemical Safety and Health

2. China National Center for Food Safety Risk Assessment

3. Beijing 100050

4. China

5. School of Food and Biological Engineering

6. Shaanxi University of Science and Technology

7. Xi'an 710021

8. Yangtze Delta Region Institute of Tsinghua University

9. Zhejiang 314006

10. Beijing Advanced Innovation Center for Food Nutrition and Human Health

11. Beijing Technology and Business University

12. Beijing 100048

Abstract

The goal of the current work was to develop a simple and sensitive high-performance liquid chromatography in combination with the fluorescence detection (HPLC-FLD) method for the fluorescence turn-on determination of cyanide and thiocyanate in swine plasma.

Funder

National Basic Research Program of China

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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