A multiplexed phospholipid membrane platform for curvature sensitive protein screening-Reference-Cited by-同舟云学术

A multiplexed phospholipid membrane platform for curvature sensitive protein screening

Published:2021 Issue:29 Volume:13 Page:12642-12650
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Berganza Eider¹^ORCID,Ebrahimkutty Mirsana P.²,Vasantham Srivatsan K.¹,Zhong Chunting¹,Wunsch Alexander³,Navarrete Alexander³,Galic Milos²^ORCID,Hirtz Michael¹^ORCID

Affiliation:

1. Institute of Nanotechnology (INT) & Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany

2. University of Münster, Robert-Koch-Straße 31, 48149, Münster, Germany

3. Institut für Mikroverfahrenstechnik (IMVT), Karlsruher Institut für Technologie (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany

Abstract

Nanoscale membrane deformations are believed to act as signaling hubs that combine geometry and lipid composition. We propose an in vitro platform for curvature sensitive protein screening using nanoparticles with phospholipid patterned on top.

Funder

Alexander von Humboldt-Stiftung

Helmholtz-Gemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D1NR01133B

Reference42 articles.

1. SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins

2. A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling