A recognition-induced three-dimensional bipedal DNA walker for highly sensitive detection of APE1-Reference-Cited by-同舟云学术

A recognition-induced three-dimensional bipedal DNA walker for highly sensitive detection of APE1

Published:2024 Issue: Volume: Page:
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Liu Qingyi¹,Zhang Qiongdan¹,Zhang Yuting¹,Tian Fanghong¹,Long Kang¹,Yang Yupei¹,Wang Wei¹^ORCID,Peng Caiyun¹²,Wang Huizhen¹^ORCID

Affiliation:

1. TCM and Ethnomedicine Innovation & Development International Laboratory, School of Pharmacy, Hunan University of Chinese Medicine, 410208, Changsha, China

2. Science & Technology Innovation Center, Hunan University of Chinese Medicine, 410208, Changsha, China

Abstract

The proposed 3D bipedal DNA walker demonstrates a highly sensitive detection capability for APE1 and holds promise for future screening of other potential APE1 inhibitors.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hunan Province

Key Research and Development Program of Hunan Province of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AY/D4AY01353K

Reference37 articles.

1. Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons

2. The APE1/REF-1 and the hallmarks of cancer

3. Aberrant expression of redox protein Ape1 in colon cancer stem cells

4. Extreme Expression of DNA Repair Protein Apurinic/Apyrimidinic Endonuclease 1 (APE1) in Human Breast Cancer As Measured by Liquid Chromatography and Isotope Dilution Tandem Mass Spectrometry

5. Mechanism of stimulation of DNA binding of the transcription factors by human apurinic/apyrimidinic endonuclease 1, APE1