Access and modulation of substituted 1-methyl-1,6-dihydropyrazolo[3,4-c]pyrazoles

Author:

Ostache Nicu-Cosmin12345ORCID,Hiebel Marie-Aude12345ORCID,Fînaru Adriana-Luminiţa6789ORCID,Allouchi Hassan1011121314,Guillaumet Gérald12345,Suzenet Franck12345ORCID

Affiliation:

1. Institut de Chimie Organique et Analytique (ICOA)

2. Université d'Orléans

3. UMR CNRS 7311

4. 45067 Orléans Cedex 2

5. France

6. Center of Applied Chemistry and Process Engineering (CAIP)

7. University “Vasile Alecsandri” of Bacau

8. Bacău

9. Romania

10. Synthèse et Isolement de Molécules BioActives (SIMBA)

11. EA 7502

12. Laboratoire de Chimie Physique

13. Université de Tours

14. 37200 Tours

Abstract

A convenient design of pyrazolo[3,4-c]pyrazoles is reported through hydrazine condensations and C–N Ullmann-type cross-coupling reactions. Chemoselective bromination followed by Suzuki–Miyaura cross-coupling reactions access to a variety of modulated heterobicycles.

Funder

Campus France

Université d'Orléans

Centre National de la Recherche Scientifique

Conseil Régional du Centre-Val de Loire

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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