Cyclotrimerization of phenylacetylene catalyzed by a cobalt half-sandwich complex embedded in an engineered variant of transmembrane protein FhuA-Reference-Cited by-同舟云学术

Cyclotrimerization of phenylacetylene catalyzed by a cobalt half-sandwich complex embedded in an engineered variant of transmembrane protein FhuA

Published:2018 Issue:30 Volume:16 Page:5452-5456
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Thiel A.¹²³⁴^ORCID,Sauer D. F.¹²³⁴^ORCID,Mertens M. A. S.⁵²³⁴,Polen T.⁶⁷⁸⁴^ORCID,Chen H.-H.⁹¹⁰¹¹,Schwaneberg U.⁵²³⁴^ORCID,Okuda J.¹²³⁴^ORCID

Affiliation:

1. Institute of Inorganic Chemistry

2. RWTH Aachen University

3. 52074 Aachen

4. Germany

5. Institute of Biotechnology

6. Institute of Bio- and Geoscience

7. IGB-1: Biotechnology

8. 52425 Jülich

9. National Kaohsiung Normal University

10. Kaohsiung

11. Taiwan

Abstract

An (η⁵-cyclopentadienyl)cobalt(i) complex was covalently incorporated in an engineered variant of the β-barrel protein FhuA. The new biohydrid catalyst cyclotrimerized phenylacetylene to give regioisomeric triphenylbenzenes.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01369A

Reference32 articles.

1. Metallopeptide catalysts and artificial metalloenzymes containing unnatural amino acids

2. Artificial Metalloenzymes for Enantioselective Catalysis Based on Biotin−Avidin

3. Artificial Metalloenzymes: Reaction Scope and Optimization Strategies

4. Artificial enzymes with protein scaffolds: Structural design and modification

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