<i>Bifidobacterium animalis</i> subsp. <i>lactis</i> CCFM1274 relieved allergic asthma symptoms by modifying intestinal tryptophan metabolism in mice-Reference-Cited by-同舟云学术

Bifidobacterium animalis subsp. lactis CCFM1274 relieved allergic asthma symptoms by modifying intestinal tryptophan metabolism in mice

Published:2024 Issue:17 Volume:15 Page:8810-8822
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Wang Hongchao¹²^ORCID,He Yuan¹²,Dang Danting¹²^ORCID,Feng Ling¹²,Huang Liming¹²,Zhao Jianxin¹²,Lu Shourong³^ORCID,Lu Wenwei¹²⁴^ORCID

Affiliation:

1. State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu 214122, China

2. School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China

3. Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu 214023, China

4. National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu 214122, China

Abstract

CCFM1274 remodeled intestinal tryptophan metabolism in mice and contributed to the improvement of allergic asthma through downregulating the levels of OVA-sIgE, IL-10 and IL-17 in BALF and upregulating the relative abundance of Bifidobacterium.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO01079E

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