A liver-immune coculture array for predicting systemic drug-induced skin sensitization-Reference-Cited by-同舟云学术

A liver-immune coculture array for predicting systemic drug-induced skin sensitization

Published:2018 Issue:21 Volume:18 Page:3239-3250
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Chong Lor Huai¹²³,Li Huan⁴⁵³,Wetzel Isaac⁶⁷⁸⁹¹⁰,Cho Hansang⁶⁷⁸⁹¹⁰^ORCID,Toh Yi-Chin¹²³¹¹²^ORCID

Affiliation:

1. Department of Biomedical Engineering

2. National University of Singapore

3. Singapore

4. School of Applied Science

5. Temasek Polytechnic

6. Department of Mechanical Engineering and Engineering Science

7. Department of Biological Sciences

8. The Nanoscale Science Program

9. Center for Biomedical Engineering and Science

10. University of North Carolina at Charlotte

11. Singapore Institute for Neurotechnology

Abstract

Recapitulation of liver-immune interactions in a microfluidic compartmentalized coculture array is sufficient to accurately predict systemic drug-induced skin sensitization.

Funder

Ministry of Education - Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2018/LC/C8LC00790J

Reference44 articles.

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2. B. Thong and D.Vervloet , Drug Allergies , World Allergy Organization , 2014

3. Quantification of Chemical Peptide Reactivity for Screening Contact Allergens: A Classification Tree Model Approach

4. Assessment of the U937 cell line for the detection of contact allergens

5. The Myeloid U937 Skin Sensitization Test (U-SENS) addresses the activation of dendritic cell event in the adverse outcome pathway for skin sensitization

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