Bicyclic acetals: biological relevance, scaffold analysis, and applications in diversity-oriented synthesis-Reference-Cited by-同舟云学术

Bicyclic acetals: biological relevance, scaffold analysis, and applications in diversity-oriented synthesis

Published:2019 Issue:5 Volume:17 Page:1037-1052
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lenci Elena¹²³⁴^ORCID,Menchi Gloria¹²³⁴⁵^ORCID,Saldívar-Gonzalez Fernanda I.⁶⁷⁸⁹¹⁰,Medina-Franco José L.⁶⁷⁸⁹¹⁰^ORCID,Trabocchi Andrea¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry “Ugo Schiff”

2. University of Florence

3. 50019 Sesto Fiorentino

4. Italy

5. Interdepartmental Center for Preclinical Development of Molecular Imaging (CISPIM)

6. School of Chemistry

7. Department of Pharmacy

8. Universidad Nacional Autónoma de México

9. Avenida Universidad 3000

10. Mexico City 04510

Abstract

The chemoinformatics analysis of fused, spiro, and bridged bicyclic acetals is instrumental for the DOS of natural product-inspired molecular collections.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB02808G

Reference144 articles.

1. Design of compound libraries based on natural product scaffolds and protein structure similarity clustering (PSSC)

2. Principles, implementation, and application of biology-oriented synthesis (BIOS)

3. Natural products as starting points for the synthesis of complex and diverse compounds

4. The re-emergence of natural products for drug discovery in the genomics era

5. Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

Cited by 34 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An Acid Catalyzed Alkynyl‐Prins Cyclization‐Rearrangement Cascade of 2‐(Alkynol)Benzoates: An Approach to 3‐Alkyl‐[n,5]‐Oxaspirophthalides;Advanced Synthesis & Catalysis;2024-08-14

2. Synthesis of the first 4-oxobutane-1,1,2,2-tetracarbonitriles containing a phenol fragment and their transformation into cyano-substituted pyrrol-2-ones showing three-position molecular switching;Organic & Biomolecular Chemistry;2024

3. Divergent access to polycyclic spiro- and fused-N,O-ketals through Bi(OTf)₃-catalyzed [4+2]-annulation of cyclic N-sulfonyl ketimines and alkynols;Chemical Communications;2024

4. Metal-Free 1,8-Diazabicyclo(5.4.0)-undec-7-ene Mediated Synthesis of α-Acetal Amides through Reaction of Glyoxylic Acid Acetalde with Aryl Isothiocyanates;Chinese Journal of Organic Chemistry;2024

5. A concise approach for the synthesis of the tetracyclic framework of Lycibarbarines A and B;Tetrahedron Letters;2023-05