The first synthesis of the antiangiogenic homoisoflavanone, cremastranone-Reference-Cited by-同舟云学术

The first synthesis of the antiangiogenic homoisoflavanone, cremastranone

Author:

Lee Bit¹²³,Basavarajappa Halesha D.⁴⁵⁶⁷⁸,Sulaiman Rania S.⁴⁵⁶⁷⁹,Fei Xiang¹²³,Seo Seung-Yong¹²³,Corson Timothy W.⁴⁵⁶⁷⁸^ORCID

Affiliation:

1. College of Pharmacy and Gachon Institute of Pharmaceutical Sciences

2. Gachon University

3. Incheon, South Korea

4. Eugene and Marilyn Glick Eye Institute

5. Department of Ophthalmology

6. Indiana University School of Medicine

7. Indianapolis, USA

8. Department of Biochemistry and Molecular Biology

9. Department of Pharmacology and Toxicology

Abstract

The homoisoflavanone cremastranone is synthesized for the first time and shown to block human retinal endothelial cell angiogenesis in vitro.

Funder

Ralph W. and Grace M. Showalter Research Trust Fund

Research to Prevent Blindness

National Center for Advancing Translational Sciences

National Research Foundation of Korea

International Retinal Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

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