Assessment of the targeting specificity of a fluorescent albumin conceived as a preclinical agent of the liver function
Author:
Affiliation:
1. Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS)
2. CNRS UMR8258 INSERM U1022
3. Université Paris Descartes
4. Sorbonne-Paris-Cité
5. Chimie ParisTech
Abstract
A liver function imaging with lactosylated labelled human albumin is introduced. Ligand and aggregates of the products are quantified before pre-clinical demonstration is achieved in a mice model of metastatic liver from colorectal cancer.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NR/C8NR04163F
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