Acid-catalyzed regioselective remote heteroarylation of alkenes via CC bond migration

Author:

Qin Shengxiang1ORCID,Zhang Yaqi1,Jiang Long2,Tse Man Kin3,Chan Albert S. C.1,Qiu Liqin1ORCID

Affiliation:

1. School of Chemistry, IGCME, The Key Laboratory of Low-Carbon Chemistry & Energy Conservation of Guangdong Province, Guangdong Provincial Key Laboratory of Chiral Molecules and Drug Discovery, Sun Yat-sen University, Guangzhou 510006, People's Republic of China

2. Instrumental Analysis and Research Centre, Sun Yat-sen University, Guangzhou 510275, People's Republic of China

3. Guangzhou Lee & Man Technology Company Limited, 8 Huanshi Avenue South, Nansha, Guangzhou 511458, People's Republic of China

Abstract

An effective path for acid-catalyzed regioselective remote heteroarylation and reductive alkylation of alkenes is reported, which exhibits excellent functional group compatibility, regioselectivity, practicality and potential applications.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

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