NS3 helicase inhibitory potential of the marine sponge <i>Spongia irregularis</i>-Reference-Cited by-同舟云学术

NS3 helicase inhibitory potential of the marine sponge Spongia irregularis

Published:2022 Issue:5 Volume:12 Page:2992-3002
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Abdelaleem Enas Reda¹,Samy Mamdouh Nabil¹^ORCID,Ali Taha F. S.²,Mustafa Muhamad³,Ibrahim Mahmoud A. A.⁴^ORCID,Bringmann Gerhard⁵^ORCID,Ahmed Safwat A.⁶,Abdelmohsen Usama Ramadan¹⁷^ORCID,Desoukey Samar Yehia¹

Affiliation:

1. Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt

2. Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt

3. Medicinal Chemistry Department, Faculty of Pharmacy, Deraya University, New Minia 61111, Egypt

4. Computational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, 61519 Minia, Egypt

5. Institute of Organic Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

6. Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt

7. Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia 61111, Egypt

Abstract

Our study discusses the anti-HCV activity of Spongia irregularis. The results revealed that the ethyl acetate fraction exhibited the highest anti-HCV activity and Nakijiquinone F is the most likely anti-HCV candidate among the screened compounds.

Funder

Minia University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D1RA08321J

Reference37 articles.

1. Structural and functional genome organization and life cycle of hepatitis C virus

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4. Role of Marine Natural Products in the Genesis of Antiviral Agents

5. Potential Antiviral Agents from Marine Fungi: An Overview

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