Transcriptomics integrated with metabolomics reveals the ameliorating effect of mussel-derived plasmalogens on high-fat diet-induced hyperlipidemia in zebrafish-Reference-Cited by-同舟云学术

Transcriptomics integrated with metabolomics reveals the ameliorating effect of mussel-derived plasmalogens on high-fat diet-induced hyperlipidemia in zebrafish

Published:2023 Issue:8 Volume:14 Page:3641-3658
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Feng Junli¹^ORCID,Chen Xi²,Wang Shitong¹,Zhang Jian¹,Wang Qingcheng³,Guo Shunyuan²,Shen Qing¹

Affiliation:

1. Zhejiang Province Joint Key Laboratory of Aquatic Products Processing, Collaborative Innovation Center of Seafood Deep Processing, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, China

2. Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang 310014, China

3. Department of Cardiology, Hangzhou Linping Hospital of Traditional Chinese Medicine, Linping 311106, Zhejiang, China

Abstract

Mussel-derived plasmalogens has a protective effect against HFD-induced hyperlipidemia. The gene-metabolite network related to the effects of Pls has been explored through the integrated analysis of hepatic transcriptome and metabolome.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO00063J

Reference59 articles.

1. Red raspberry extract (Rubus idaeus L shrub) intake ameliorates hyperlipidemia in HFD-induced mice through PPAR signaling pathway

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