Platinum-loaded, selenium-doped hydroxyapatite nanoparticles selectively reduce proliferation of prostate and breast cancer cells co-cultured in the presence of stem cells-Reference-Cited by-同舟云学术

Platinum-loaded, selenium-doped hydroxyapatite nanoparticles selectively reduce proliferation of prostate and breast cancer cells co-cultured in the presence of stem cells

Published:2020 Issue:14 Volume:8 Page:2792-2804
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Barbanente Alessandra¹²³⁴,Nadar Robin A.⁵⁶⁷⁸⁹,Esposti Lorenzo Degli¹⁰¹¹¹²⁴^ORCID,Palazzo Barbara¹³¹⁴⁴,Iafisco Michele¹⁰¹¹¹²⁴^ORCID,van den Beucken Jeroen J. J. P.⁵⁶⁷⁸⁹,Leeuwenburgh Sander C. G.⁵⁶⁷⁸⁹^ORCID,Margiotta Nicola¹²³⁴^ORCID

Affiliation:

1. Dipartimento di Chimica

2. Università degli Studi di Bari Aldo Moro

3. 70125 Bari

4. Italy

5. Department of Dentistry – Regenerative Biomaterials

6. Radboud Institute for Molecular Life Sciences

7. Radboud University Medical Center

8. 6525 EX Nijmegen

9. The Netherlands

10. Institute of Science and Technology for Ceramics (ISTEC)

11. National Research Council (CNR)

12. 48018 Faenza

13. Ghimas S.p.A.

14. 73100 Lecce

Abstract

Selenite-doped hydroxyapatite nanoparticles loaded with an anti-tumor Pt(ii)–pyrophosphate complex were prepared to treat bone tumors and metastases by local release of multiple chemotherapeutic agents.

Funder

Radboud Universitair Medisch Centrum

Universita degli Studi di Bari Aldo Moro

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/D0TB00390E

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1. Osteosarcoma treatment – Where do we stand? A state of the art review

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