Hydrogel particles-on-chip (HyPoC): a fluorescence micro-sensor array for IgG immunoassay

Author:

De Masi Alessandra12,Scognamiglio Pasqualina Liana1,Battista Edmondo13,Netti Paolo Antonio132,Causa Filippo132ORCID

Affiliation:

1. Center for Advanced Biomaterials for Healthcare@CRIB, Istituto Italiano di Tecnologia (IIT), Largo Barsanti e Matteucci 53, 80125 Naples, Italy

2. Dipartimento di Ingegneria Chimica del Materiali e della Produzione Industriale (DICMAPI), University “Federico II”, Piazzale Tecchio 80, 80125 Naples, Italy

3. Interdisciplinary Research Centre on Biomaterials (CRIB), University “Federico II”, Piazzale Tecchio 80, 80125 Naples, Italy

Abstract

A micro-biosensor based on hydrogel microparticles integrated in a microfluidic portable device is developed to tune the LOD and dynamic range, while reducing incubation time and reagent volume.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Reference60 articles.

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3. IgG (Total) Human ELISA Kit - Invitrogen, https://www.thermofisher.com/elisa/product/IgG-Total-Human-ELISA-Kit/BMS2091 , (accessed 5 February 2023)

4. N.America , Human IgG total Ready-SET-Go! ® Human IgG total Ready-SET-Go! ELISA Europe/International* Human IgG total ELISA Ready-SET-Go!® Catalog Number: 88–50550 RUO: For Research Use Only, vol. 642

5. Human IgG, Total, ELISA kit, https://www.cygnustechnologies.com/human-igg-total-elisa-kit.html , (accessed 7 June 2021)

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