Mechanistic insights into Smiles rearrangement. Focus on π–π stacking interactions along the radical cascade

Author:

Khartabil Hassan1234,Doudet Ludovic1234ORCID,Allart-Simon Ingrid1234,Ponce-Vargas Miguel1234ORCID,Gérard Stéphane1234ORCID,Hénon Eric1234ORCID

Affiliation:

1. Institut de Chimie Moléculaire de Reims UMR CNRS 7312

2. Université de Reims Champagne-Ardenne

3. Reims Cedex 02 BP39

4. France

Abstract

The synthesis of new arene and heteroarene scaffolds of therapeutic interest has generated a renewed interest in the domino radical cyclisation–Smiles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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