Stereoselective quantitative analysis of ranolazine in plasma and tissue samples: application in pharmacokinetics and tissue distribution studies-Reference-Cited by-同舟云学术

Stereoselective quantitative analysis of ranolazine in plasma and tissue samples: application in pharmacokinetics and tissue distribution studies

Published:2022 Issue:34 Volume:46 Page:16547-16555
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Zhu Yuanyuan¹,Zhang Hong²^ORCID,Ma Siman¹,Miao Lizhi³,Jin Ge⁴,Li Jiahui⁵,Nuerkaman Tohutanguli⁵,Sun Qiruo¹,Liu Yang⁴,Yin Shiliang⁴

Affiliation:

1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, China

2. School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenyang 110016, China

3. Safety Evaluation Center of Shenyang SYRICI Testing Co., Ltd., Shenyang 110141, China

4. School of Pharmacy, Shenyang Medical College, No. 146 Huanghe North Street, Shenyang, Liaoning, 110034, China

5. School of Business Administration, Shenyang Pharmaceutical University, Shenyang 110016, China

Abstract

This study aimed to develop a rapid and sensitive reversed-phase mode high-performance liquid chromatography-electrospray ionization coupled with a tandem mass spectrometry method for the simultaneous determination of ranolazine enantiomers in rat plasma and tissues.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ02302D

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