Iron–sulfur cluster biosynthesis and trafficking – impact on human disease conditions
Author:
Affiliation:
1. Department of Chemistry and Biochemistry
2. The Ohio State University
3. Columbus
4. USA
5. The Ohio State Biochemistry Program
6. The Biophysics Graduate Program
Abstract
Iron–sulfur cluster biogenesis and trafficking enables the function of a number of cellular proteins. As such, mutations or perturbations in these pathways lead to disease states.
Funder
National Institutes of Health
Publisher
Oxford University Press (OUP)
Subject
Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)
Link
http://pubs.rsc.org/en/content/articlepdf/2018/MT/C7MT00180K
Reference233 articles.
1. Iron –sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery
2. Iron–sulfur cluster biogenesis and trafficking in mitochondria
3. Biogenesis and functions of mammalian iron-sulfur proteins in the regulation of iron homeostasis and pivotal metabolic pathways
4. Emerging critical roles of Fe–S clusters in DNA replication and repair
5. Mitochondrial iron–sulfur protein biogenesis and human disease
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