Enantioselective synthesis of tetrahydroisoquinolines via catalytic intramolecular asymmetric reductive amination-Reference-Cited by-同舟云学术

Enantioselective synthesis of tetrahydroisoquinolines via catalytic intramolecular asymmetric reductive amination

Published:2021 Issue:9 Volume:8 Page:1930-1934
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liu Ruixia¹²³⁴,Han Jingkuo¹²³⁴,Li Bin⁵⁶⁷⁸⁹,Liu Xian¹⁰¹¹⁴,Wei Zhao¹²³⁴,Wang Jiaxin¹²³⁴,Wang Qiaofeng¹²³⁴¹²,Jiang Ru¹²³⁴^ORCID,Nie Huifang¹²³⁴^ORCID,Zhang Shengyong¹²³⁴

Affiliation:

1. School of Pharmacy

2. Fourth Military Medical University

3. Xi'an

4. PR China

5. Key Laboratory of Resource Biology and Biotechnology in Western China

6. Ministry of Education

7. The College of Life Sciences

8. Northwest University

9. Xi'an 710069

10. Beijing Institute of Radiation Medicine

11. Beijing

12. Xi'an Peihua University

Abstract

A highly efficient intramolecular asymmetric reductive amination transformation catalyzed by an iridium complex of ^tBu-ax-Josiphos has been realized, providing an efficient access to various THIQ alkaloids.

Funder

Key Research and Development Projects of Shaanxi Province

Natural Science Basic Research Program of Shaanxi Province

Fourth Military Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D0QO01554G

Reference45 articles.

1. Recent Advances in Reductive Amination Catalysis and Its Applications