Palladium catalyzed C–C and C–N bond forming reactions: an update on the synthesis of pharmaceuticals from 2015

Palladium catalyzed C–C and C–N bond forming reactions: an update on the synthesis of pharmaceuticals from 2015–2020

Published:2021 Issue:2 Volume:8 Page:384-414
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Rayadurgam Jayachandra¹²³⁴⁵^ORCID,Sana Sravani⁶⁷⁸⁹,Sasikumar M.¹⁰¹¹¹²⁹,Gu Qiong¹²³⁴⁵^ORCID

Affiliation:

1. Research Center for Drug Discovery

2. School of Pharmaceutical Sciences

3. Sun Yat-Sen University

4. Guangzhou 510006

5. People's Republic of China

6. Alder Research Chemicals Private Limited

7. CSIR-IICT

8. Hyderabad

9. India

10. Department of Chemistry

11. Indian Institute of Science Education and Research

12. Tirupati

Abstract

Some of the most prominent and promising catalysts in organic synthesis for the requisite construction of C–C and C–N bonds are palladium (Pd) catalysts, which play a pivotal role in pharmaceutical and medicinal chemistry.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D0QO01146K

Reference190 articles.

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3. The role of the medicinal chemist in drug discovery — then and now

4. J. Magano and J. R.Dunetz , Transition Metal-Catalyzed Couplings in Process Chemistry: Case Studies from the Pharmaceutical Industry , Wiley-VCH , Weinheim , 2013

5. Transition Metal Catalyzed Coupling Reactions under C−H Activation

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