A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer-Reference-Cited by-同舟云学术

A robust photoluminescence screening assay identifies uracil-DNA glycosylase inhibitors against prostate cancer

Published:2020 Issue:7 Volume:11 Page:1750-1760
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Li Guodong¹²³⁴,Henry Stuart Adam⁵⁶⁷⁸,Liu Hao⁵⁹¹⁰¹¹,Kang Tian-Shu¹²³⁴,Nao Sang-Cuo¹²³⁴,Zhao Yichao¹²¹³¹⁴¹⁵,Wu Chun⁵⁹¹⁰¹¹,Jin Jianwen¹²¹³¹⁴¹⁵,Zhang Jia-Tong¹²³⁴,Leung Chung-Hang¹²³⁴^ORCID,Wai Hong Chan Philip⁵⁶⁷⁸¹²^ORCID,Ma Dik-Lung⁵⁹¹⁰¹¹^ORCID

Affiliation:

1. State Key Laboratory of Quality Research in Chinese Medicine

2. Institute of Chinese Medical Sciences

3. University of Macau

4. Macau

5. Department of Chemistry

6. University of Warwick

7. Coventry CV4 7AL

8. UK

9. Hong Kong Baptist University

10. Kowloon Tong

11. Hong Kong

12. School of Chemistry

13. Monash University

14. Clayton

15. Australia

Abstract

The discovery of UDG inhibitors against prostate cancer by using a robust photoluminescence screening assay that can avoid false negatives arising from the background fluorescence.

Funder

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Health and Medical Research Fund

Universidade de Macau

Hong Kong Baptist University

National Natural Science Foundation of China

Australian Research Council

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry