In vitro cytotoxicity and in vivo zebrafish toxicity evaluation of Ru(ii)/2-mercaptopyrimidine complexes

Author:

Velozo-Sá Vivianne S.12345ORCID,Pereira Luciano R.6785ORCID,Lima Aliny P.9105ORCID,Mello-Andrade Francyelli12345ORCID,Rezende Manuela R. M.12345ORCID,Goveia Rebeca M.12345ORCID,Pires Wanessa C.12345ORCID,Silva Monize M.6785ORCID,Oliveira Katia M.6785ORCID,Ferreira Antonio G.6785ORCID,Ellena Javier1112135ORCID,Deflon Victor M.1412135ORCID,Grisolia Cesar Koppe151621718ORCID,Batista Alzir A.6785ORCID,Silveira-Lacerda Elisângela P.12345ORCID

Affiliation:

1. Laboratory of Molecular Genetics and Cytogenetics

2. Institute of Biological Sciences

3. Federal University of Goias-UFG

4. CEP 74690-900 Goiania

5. Brazil

6. Department of Chemistry

7. Federal University of Sao Carlos

8. São Carlos (SP)

9. Faculty of Brazil Institute

10. Anapolis

11. Physics Institute of Sao Carlos

12. University of Sao Paulo

13. Sao Carlos

14. Chemistry Institute

15. Laboratory of Toxicological Genetics

16. Department of Genetics and Morphology

17. University of Brasilia

18. Brasilia

Abstract

Ru(ii)/2-mercaptopyrimidine complexes active against cancer cells did not present toxic effects during embryonic and larval development of zebrafish.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Financiadora de Estudos e Projetos

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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