Local transplantation of GMSC-derived exosomes to promote vascularized diabetic wound healing by regulating the Wnt/β-catenin pathways-Reference-Cited by-同舟云学术

Local transplantation of GMSC-derived exosomes to promote vascularized diabetic wound healing by regulating the Wnt/β-catenin pathways

Published:2023 Issue:3 Volume:5 Page:916-926
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Liu Ziwei¹²³^ORCID,Yang Shuo²^ORCID,Li Xiaoming⁴,Wang Situo¹²³,Zhang Tong²,Huo Na²,Duan Ruixin⁵,Shi Quan²,Zhang Jianjun⁴^ORCID,Xu Juan²

Affiliation:

1. Medical School of Chinese PLA, Beijing, 100853, China

2. Department of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing, 100853, China

3. Orthopedic Laboratory of PLA General Hospital, Beijing, 100853, China

4. College of Chemical Engineering, Beijing University of Chemical Technology, Beijing, 100029, China

5. Department of Stomatology, The People's Hospital of Anyang City, Henan, 455000, China

Abstract

GMSCs-Exo promote proliferation, migration, and tube formation of HUVECs by regulating the Wnt/β-catenin signalling pathway in a high-glucose environment. GMSCs-Exo were loaded and delivered via PHE microspheres, novel porous microscaffolds with superb biocompatibility.

Funder

Natural Science Foundation of Beijing Municipality

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NA/D2NA00762B

Reference42 articles.

1. Wound healing

2. Strategy for Treatment of Infected Diabetic Foot Ulcers